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Desoto, MO Hotels

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Featured Desoto Hotels


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4.6/5 241 reviews

4800 US Highway 67, Desoto

63020, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-636-5867448



5.79 mi (9.32km) from City Center
  • Pool
  • Wireless Internet
  • No Pets Allowed
  • Health/Fitness Center
  • Full Kitchen
  • Pool
  • Wireless Internet
  • No Pets Allowed
  • Health/Fitness Center
  • Full Kitchen
  • Business Center
  • Parking Included
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Holiday Inn Express & Suites Festus - South St. Louis in Desoto, Missouri
Holiday Inn Express & Suites Festus - South St. Louis in Desoto, Missouri

4.8/5 1312 reviews

1802 Gamel Cemetery Road, Festus

63028, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-636-9377100



9.16 mi (14.74km) from City Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • Kids Eat Free
  • No Pets Allowed
  • Parking Included
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4.6/5 1088 reviews

820 Market Street, Farmington

63640, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-573-7010505



24.84 mi (39.97km) from City Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • No Pets Allowed
  • Parking Included
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4.4/5 2127 reviews

4901 Six Flags Road, Eureka

63025, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-636-9386661



26.2 mi (42.16km) from City Center
  • Indoor Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Health/Fitness Center
  • Indoor Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Health/Fitness Center
  • Holidome
  • Kids Eat Free
  • Parking Included
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4.8/5 1161 reviews

4250 Midamerica Lane, St. Louis

63129, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-314-8940700



26.24 mi (42.22km) from City Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Business Center
  • Health/Fitness Center
  • No Pets Allowed
  • Parking Included
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4.5/5 1536 reviews

1848 Bowles Ave, Fenton

63026, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-636-3494444



28.03 mi (45.1km) from City Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Free Breakfast
  • Indoor Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Kitchenette
  • Kids Eat Free
  • Health/Fitness Center
  • Parking Included
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4.0/5 1893 reviews

10709 Watson Road, St. Louis

63127, United States

Reservations 1 888 HOLIDAY (1 888 465 4329)

Front Desk 1-314-8216600



29.79 mi (47.93km) from City Center
  • Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Health/Fitness Center
  • Pool
  • Wireless Internet
  • Pets Allowed
  • Business Center
  • Health/Fitness Center
  • Kids Eat Free
  • Parking Included
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Planning your stay in Desoto

Whether it's your first visit or Desoto is a favorite travel destination, get ready to explore all that Desoto has to offer and find the perfect temporary home base with help from IHG. Compare the best hotels in Desoto by reading through 9358 reviews from verified hotel guests. When you book your room with IHG, you're assured a great deal and lowest rate with our Best Price Guarantee. We boast 7 hotels in Desoto, MO, all with a distinctive flair and a variety of amenities, and you can conveniently narrow down your choices and book your room directly with us.

No matter if you're travelling to Desoto to attend a conference, unwind on vacation, or enjoy a romantic weekend getaway, we have you covered. And if your travels take you to another part of the world, you'll find an IHG accommodation that meets your needs. From hotels in the heart of it all to luxury accommodations off the beaten path, IHG offers great hotel deals in Desoto and throughout the world.

Enter your travel dates to view the best offers on hotel accommodations, and use our advanced search features to find the hotels with the amenities you desire. When you stay as an IHG Rewards Club member, you also enjoy free in-hotel Internet access. Some of our hotels boast indoor swimming pools, while others offer hot breakfast, in-room kitchens, and spa services. We make it easy to book the perfect hotel for your trip.

More about IHG Hotels near Desoto

Top Rated Desoto Hotels


Comfortable stay
By IHG vacation traveler
Nice accommodations with a good breakfast and a friendly staff. [Less]
Convenient
Recommend for location and pricing. Could use update for the rooms and bathrooms, but overall good compared to other options in immediate area. [Less]
A good place to stay
By Craig MD
This is a will maintained hotel with an attentive and friendly staff. The rooms are clean and comfortable. The breakfast is always good and we'll stocked. There is a gym and a pool that are well [More] maintained. [Less]
Beautiful and spacious
By SamRoute66
Beautiful hotel. Love the spacious areas to sit and relax that are outside of the actual room [Less]
Cabanas make all the difference
By Roovy
The pool, outdoor amenities, and gym were all things that made this location one of the best I have stayed at! [Less]
Route 66 Hotel during Missoura's Tour
By Ioway Jim
Hotel, itself is fine. But it is a work in progress. Breakfast is only for a fee. Employees are knowledgeable and gracious. Room is nicely appointed, bathroom is functionally setup. Not recommended [More] until renovation is completely, due to current food setup. [Less]
Decent hotel
By GuneaPig
The room was nice, spacious, and comfortable. The smell of the cleaning products used was a little strong and some more attention could've been payed to the bathroom. But overall I would stay here [More] again. [Less]
Clean spacious room excellent front desk staff
By Pop5!
Room was clean and spacious. Larger room with plenty of space to move around in. Front desk staff were excellent. Breakfast entrees were great! Pillows were awesome. Breakfast employee was very nice [More] and friendly to the guests. [Less]
Enjoyable Stay
By gdub2
Enjoyable weekend stay with a grocery store, movie theater and numerous restaurants nearby. Quality breakfast selection, clean and well kept location [Less]

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