National Shrine of Our Lady of the Miraculous Meda
1805 W Saint Joseph St, Perryville, Missouri 63775
Saint Mary's of the Barrens Historic District was founded in 1818; the church was started in 1827. The Shrine was built in 1929 to honor our Lady of the Miraculous Medal. The church is modeled after the Vincentian Motherhouse chapel in Rome, Monte Citorio. The church is decorated with paintings and has intricate design work on the walls and ceilings. It is a national center for Marian devotion.