The hotel enjoys a prime location at Gulou Square in Gulou District, surrounded by bustling attractions including Xuanwu Lake, Jimi Temple, 1912 Bar Street, the Ming Dynasty City Wall, Hunan Road Shiziqiao Food Street, and Xinjiekou Commercial Street. Perched at the city's highest vantage point, the hotel offers panoramic views.

Designed by SOM—the world-renowned architectural firm led by Adrian Smith, the “pioneer of skyscraper design”—the InterContinental Nanjing occupies the iconic Zifeng Tower, soaring nearly 450 meters high. Its exterior features a groundbreaking triangular glass curtain wall that spirals upward like dragon scales.