Holiday Inn Express & Suites St. Louis - Chesterfield

Holiday Inn Express® & Suites St. Louis–Chesterfield offers a modern, comfortable stay for business and leisure travelers. Conveniently located just off Interstate 64 at Exit 17, our Chesterfield, Missouri hotel is approximately 23 miles west of downtown St. Louis, providing easy access to the entire metro area.

Our well appointed guest rooms are designed for comfort, productivity, and relaxation, complemented by friendly, attentive service throughout your stay.

Business travelers value our proximity to leading employers and healthcare centers, including St. Luke’s Hospital, Mercy Hospital, Barnes Jewish Hospital, Pfizer, Centene, Bayer, Amdocs, and Spirit of St. Louis Airport, making our hotel ideal for corporate, medical, and project based travel.

Guests also enjoy easy access to popular area attractions such as Six Flags St. Louis, Gateway Motorsports Park, Anheuser Busch Brewery, The District at Chesterfield, St. Louis Premium Outlets, the Gateway Arch, St. Louis Zoo, Topgolf, and The Factory concert venue.

The hotel features 91 spacious guest rooms and amenities including free high speed Wi Fi, an indoor pool, fitness center, 24/7 business center, flexible meeting space, and a complimentary Express Start™ breakfast served daily.

Enjoy a convenient, welcoming stay at Holiday Inn Express® & Suites St. Louis–Chesterfield, your home base in Chesterfield, Missouri.