Buffalo International Airport (BUF) : I-90 E/NEW YORK STATE THRUWAY E toward I-290/NIAG FALLS/ALBANY I-290 W/YOUNGMANN EXPY EXIT 50 toward NIAGARA FALLS I-190 N toward NIAGARA FALLS (Portions toll) (Crossing into CANADA) QEW TORONTO Take ONTARIO STREET Exit 327 ONTARIO STREET is on the RIGHT.
John C. Munroe Hamilton International Airport (YHM) : Left at Airport Rd 3rd LEFT onto UPPER JAMES ST LINCOLN M ALEXANDER PKWY E to RED HILL VALLEY PARKWAY Take QEW toward NIAGARA Take RR-42/ONTARIO STREET exit, EXIT 47 Turn RIGHT Ontario Street- Hotel on Right
Toronto Lester B. Pearson International Airport (YYZ) : PROVINCIAL ROUTE 427 S QEW toward HAMILTON Ontario Street EXIT 47 Turn RIGHT onto RR-42/ONTARIO ST 327 ONTARIO STREET is on the RIGHT.

WEST on GENESEE ST toward LUIZ F KAHL WAY LEFT onto RT 33 W I 90 E NEW YORK STATE THRUWAY E toward I 290 NIAG FALLS ALBANY I 290 W YOUNGMANN EXPY via EXIT 50 toward NIAGARA FALLS I 190 N NIAGARA FALLS becomes QUEENSTON LEWISTON BRIDGE QEW TORONTO ONTARIO STREET exit 47, turn right

From Peace Bridge and follow the QEW to St. Catharines. Take exit 47, Ontario St.cut off and make a right onto the Service Road and right again at lights to get on Ontario Street. Holiday Inn is 3 blocks on your right hand side

From Rainbow Bridge take QEW. Take the QEW to St. Catharines. Take Exit 47 Ontario Street cut off and make a right onto the Service Road and right at lights to get on Ontario Street. You will see the Holiday Inn 3 blocks up on your right hand side

From the Toronto Airport, merge onto Hwy 427 South 6.4 miles, then merge onto the QEW toward Hamilton. Take Exit 47 Ontario Street. You will find the Hotel 3 blocks up on your right hand side