Kansas City International Airport (MCI) (MCI) : I-435 East from airport Exit at Ambassador by turning right (south) Hotel will be on right side
Charles Wheeler Downtown Airport (MKC) : I-29 North to 112th Street exit Turn right (east) on 112th Street At first light, turn left (north) on Ambassador Hotel will be on your left

I 29 south exit 13 turn left on D highway drive to Ambassador Drive, turn right hotel located on right.

Interstate 29 north to exit 12 which is 112th Street. Turn right on exit 12, go to stop light Ambassador Drive. Turn left at stop light, hotel will be a quarter mile down on the left.

Interstate 29 North to the 112th Street Exit. Go east to Ambassador Drive then head north to the Holiday Inn on the left West side of the street.

Interstate 70 East to Interstate 29 North to exit 12 which is 112th street Exit. Turn right on 112th street. Take your first left on Ambassador Drive and the Hotel will be located on the left side of Ambassador approximately .5 miles up the street. The hotel is located next to KCI EXPO center.