St. Louis Lambert International (STL) : From St. Louis Lambert International Airport take I-70 West 4 miles and merge on I-270 South, Exit #232. Continue on I-270 South for 20 miles and take I-55 South, exit 1A. Follow I-55 South for 1.8 miles and exit at Butler Hill Road, #195. Turn left on Butler Hill Road for 2 blocks and turn right on Midamerica Plaza Drive for one block and then right on Midamerica Lane, hotel on your left.
I 55 south to exit 195 at Butler Hill Road. Turn left at the light and go east for one block then turn right on Midamerica Plaza drive into the hotel complex.
I 55 north to exit 195, turn right on Butler Hill road then another right into the hotel complex.
I 255 south from either I 70 or I 64, follow 255 south from Illinois into Missouri and exit on I 55 south. Follow I 55 for two miles and exit 195 at Butler Hill, turn left at the light and one block to a right on Midamerica Plaza.
I 70 east bound towards St. Louis then take I 270 south for 20 miles. Take I 55 south exit for two miles to Butler Hill Road. Turn left on Butler Hill for one block and turn right into hotel complex on Midamerica Plaza.