Name: Vignette Collection Hotel Spero
Address: 405 Taylor Street, San Francisco, CA, 94102, United States
Telephone: 1-415-8852500
Price range: $$$ - Best Price Guarantee When You Book Direct

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Hotel Spero,

Vignette Collection

United States

Hotel Spero

Historic San Francisco, Boutique Hotel Charm

At Hotel Spero, discover a distinctive retreat tucked into the heart of vibrant Union Square. Steps from San Francisco’s most iconic neighborhoods, dining, attractions, and culture, the city unfolds just outside our hotel doors. Stroll to the Powell Street cable cars, enjoy a show in the Theater District or explore nearby Nob Hill and North Beach.

Inside, historic character blends effortlessly with modern design, creating a refined yet relaxed place to settle in, recharge, and explore. Whether you’re wandering the city for a weekend escape, savoring a slower stay, a business meeting or a meaningful celebration, Hotel Spero offers an inviting setting shaped by warmth, style, and intentional hospitality.

405 Taylor Street, San Francisco, CA 94102 United States

Contact Front Desk:
+1-415-8852500

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Hotel Highlights

A Curated Journey Through San Francisco
Stylish Slumber
Elevate Your Next Meeting or Event
Discover Artisanal Brews at Jasper's Corner
Embrace Union Square and San Francisco

A Curated Journey Through San Francisco

Experience San Francisco through curated itineraries that seamlessly blend iconic attractions, colorful neighborhoods, and exclusive local discoveries.

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Stylish Slumber

Relax in the sanctuary of our luxury San Francisco hotel rooms with warm lighting, and plush textiles. Chic geometric forms converge with cool designs and upscale touches to create a welcoming oasis.

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Elevate Your Next Meeting or Event

Perfectly crafted for hosting everything from an intimate dinner for 80 to a chic reception for 140, these spaces are meticulously designed to forge encounters as iconic as you. Our 3,000 square feet of Union Square meeting space is modern and versatile.

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Discover Artisanal Brews at Jasper's Corner

From elevated gastropub classics to cleverly crafted breakfast favorites, our eclectic award-winning menus dish out fusion-inspired flavor and organic ingredients that also cater to vegetarian palates.

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Embrace Union Square and San Francisco

Check in the heart of San Francisco. Our Union Square hotel's location offers effortless access to the city’s top attractions, cultural landmarks, and scenic sights. Enjoy easy access to the Chase Center, Chinatown, Market Street and the best of downtown.

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Take a look inside

Lobby of Hotel Spero in Union Square San Francisco

Vignette Hotel Spero lobby

Hotel Lobby

Pet Friendly

Guest Room

Urban Suite living and dining areas at Hotel Spero in Union Square

Guest Room

Fitness Center featuring Peloton

Californian meeting room in Hotel Spero Union Square

Californian meeting space in San Francisco with U-shape setup

Exterior entrance of Hotel Spero in Union Square San Francisco

Catering to your every need

Our amenities and services are designed to ensure your stay is complete and you have easy access to the things you may need while you travel.

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Hotel packages available

Prices shown reflect an average per night stay from

Additional Offers

Carefully crafted accommodations

Standard

Our king rooms, recently upgraded, now feature luxurious glass-enclosed showers set against Spanish-tiled bathrooms, blending style and comfort. Each spacious room is elegantly furnished with a plush king-sized bed, a well-lit workspace, and oversized picture windows that bathe the space in natural

Suite

Include Serenity Suites, Urban Suites and one Bedroom Suites. All larger rooms with hardwood floors, 50 inch Television, WIFI, bath amenities, slippers, in-room safe, iron and ironing board, and a mini refrigerator.

{accoladesSource=TripAdvisor, accoladesTitle=Amazing customer service}

6191 - Hotel Accolade Source

Insights from our guests

Amazing customer service

TripAdvisor

Explore the extraordinary

San Francisco's Union Square is the teeming commercial hub of the city. A variety of shops and restaurants are packing into the area surrounding the actual square. Tourists huddle to view one the city's most unique sites, the manual cable car turnaround.

local attractions