Jacksonville International Airport (JAX) : Take I-10 West miles. Transfer to I-75 South. Take Exit #427 Lake City US 90. Left off exit ramp onto US 90. Right at 2nd light onto Commerce Dr. Hotel on left.
Gainesville Regional Airport (GNV) : Head NE onto 52nd Dr. Left onto 49th Ave. Left onto SR24 (Waldo Rd). Right onto 39th Ave. Right onto 6th St. Merge onto US 441 N. Take ramp I-75 N. Take Exit 427. Right off ramp onto US 90. First right onto Commerce Dr. Hotel on Left.