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Holiday Inn St Louis SW - Route 66

10709 Watson Road, St. Louis, MO 63127 United States  Get Directions

Check-In: 3PM

Check-Out: 11AM

Minimum Check-In Age:  21


Contact Front Desk: 1-314-8216600

St. Louis hotel along the historic Route 66

Get Your Kicks on Route 66

Welcome to our fully renovated hotel & conference center, completed in 2023! Full-service, free parking & pet friendly! Our property features room to spread out in a vibrant lobby with spaces to gather, relax & work. The all new courtyard boasts a heated pool, cabanas & fireplaces with cozy seating & plenty of natural light to feel refreshed! Enjoy yard games under the string lights on the patio or workout in our new fitness center overlooking it all!

Located on historic Route 66 at highway I-44 & I-270, just 14 miles from the Gateway Arch! We are centrally located to everything St. Louis has to offer & are minutes from top attractions: experience a St. Louis CITY SC game at CITYPARK, visit the St. Louis Zoo, Science Center, Missouri Botanical Gardens, Magic House, Six Flags or World Wide Technology Soccer Park


The hotel is just a short drive to Webster University, Harris-Stowe, St. Louis University & Washington University. Just a few miles to top medical centers, Barnes Jewish Hospital, St. Louis Children's Hospital, SSM, & Mercy Hospitals


Welcoming all travelers to our 213-room hotel & 15,000 sf of space for your next event. Sunset Event Space, operated by Twisted Tree, is the perfect spot to book your wedding or special event


Start your day at Wakey Wakey & then enjoy lunch or dinner at Award-winning Twisted Tree Steakhouse adjacent to the hotel.


Amenities & Services

Kids Eat Free
Kids Eat Free
Pets allowed
Pets allowed
Fitness center
Fitness center
Wi-Fi included
Wi-Fi included
Holiday Inn Hotel Rooms

Rest and Recharge in Comfort

The Holiday Inn Route 66 offers comfortable guestrooms, stylish and contemporary. From perks like free high-speed Internet access and a 42-inch television to a large work desk and chair, we have everything you need for a comfortable stay.

holidayinn hotel dining

Enjoy Delicious Dining Options

Located on property, Wakey Wakey a Breakfast Place and Twisted Tree Steakhouse, click link for menu and hours of operation. Less than a quarter of a mile from the Hotel, Helen Fitzgerald's Irish Grill & Pub is open daily

Kids eat and stay free

Kids Stay and Eat Free!

Kids ages 18 and under stay for free when sharing their parents’ room. Up to 2 kids ages 11 and under eat free per adult ordering from the main menu in any Holiday Inn® on-site restaurant. Up to 4 kids per dining party.

FAQs for Holiday Inn St Louis SW - Route 66

Yes, Holiday Inn St Louis SW - Route 66 has an outdoor pool.
Pets are welcome at Holiday Inn St Louis SW - Route 66. There is a pet deposit per stay of 35 USD . Our Pet Policy: We are pet friendly and accept pets up to 40 pounds with certain restrictions. A thirty five dollar nonrefundable pet cleaning fee will be charged for the duration of your stay..
Complimentary parking is available at Holiday Inn St Louis SW - Route 66 for hotel guests.
Always check the hotel's cancellation policy before booking a rate. Room cancellation is subject to rate booked at time of reservation and cancellation policy varies by rate.
Holiday Inn St Louis SW - Route 66 has 2 restaurants.
Check-in at Holiday Inn St Louis SW - Route 66 is from 3PM, and check-out time is 11AM. Contact the hotel directly for options available for early check-in or late check-out.
Yes, there is an onsite fitness center at Holiday Inn St Louis SW - Route 66.
Yes, the Holiday Inn St Louis SW - Route 66 offers free WiFi!
Read more FAQs
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All of our hotels use the IHG Green Engage system, an innovative online environmental sustainability system that gives our hotels the means to measure and manage their impact on the environment. It’s our way of making sure we’re protecting our surroundings for our guests today, and tomorrow.