We have recently renovated our lobby and guest rooms.
Explore Our Hotel
Durham, NC Hotel Near Duke University Medical Center
With an ideal location along I-85 and the Durham Freeway, and a free shuttle service to Duke University Medical Center, Duke University Hospital, and area medical facilities, the Holiday Inn Express® Durham hotel offers clean, newly renovated guest rooms, comfort and convenience for your next trip. We pride ourselves on being a Home Away From Home for our guests by offering great service at an affordable price.
Our hotel near Duke University is just minutes from Treyburn Corporate Park and has everything you need for a productive stay in Durham, NC. Use the complimentary Wi-Fi access or our business center to keep in touch with home and the office.
Our hotel is also ideal for visiting NC Central, NC School of Science and Math, and UNC Chapel Hill. There are a number of attractions to see on Duke University campus, including Duke Chapel, Nasher Museum of Art and Sarah P Duke Gardens. In town, catch a Durham Bulls game or see a show at Durham Performing Arts Center. The North Carolina Museum of Life and Science is a place where children have fun learning, and our hotel near Eno River State Park is ideal for hikers and paddlers alike.
You are sure to feel at home in our clean, comfortable and newly renovated accommodations. Enjoy a free, hot breakfast buffet, sparkling outdoor pool and our new Fitness Center. Call today, and let our Durham hotel exceed your expectations!
- Black-out Shades
- Rollaway Bed/Cot Available
- Crib Available
- Iron/Ironing Board
- In-room Safe
- Separate Hanging Closet
- In-Room Heating and A/C Controls
- Extra Bedding Available
- Sofa Bed/Sleeper Couch
- Private Bathroom
- Bathroom Amenities Available
- Hair Dryer
- Mini Refrigerator
- Coffee Maker
- Flat-screen TV
- Work Desk with Lamp
- Desk-level Electrical Outlet
- Free Local Calls
- Premium Channels
- Direct-dial Phone
- Two-line Phone
- Phone with Voicemail
- Complimentary Coffee/Tea Supplies
- Full Breakfast Included
- Breakfast Buffet Included
- Continental Breakfast Included
- Complimentary Coffee in Lobby
- Kids Eat Free
- Off-site Restaurant Delivery Available
- On-Site Business Center
- Office supplies available
- Free High-Speed Internet in all Rooms
- Wireless Internet service is free for all IHG® Rewards Club members
Entertainment & Recreation
- Outdoor Pool
- Outdoor Pool Hours of Operation: 10:00 AM - 10:00 PM
- Pool Open from: 31-May-2019 to 15-September-2019
Health & Fitness
Last Renovation of Fitness Center Equipment: 2020
Housekeeping & Laundry
- Daily Housekeeping
- Language Interpretation
- Wake Up Calls
- Ice Machine
2516 Guess Road
Durham, North Carolina 27705
Check In: 3:00 PM
Check Out: 12:00 PM
Check-in Age: 21
Parking + -
- Complimentary Self Parking Available
Shuttle + -
Accessibility + -
- Public Entrance
- Guest Rooms
- Public Restrooms
- Registration Desk
- Business Center
- Number of Accessible Meeting Rooms: 0
Accessible Hotel Areas
- Registration Area
- Accessible Guest Rooms
- Business Center
Hotel Areas with Accessible Routes from Accessible Public Entrance
- Accessible Self Parking
- Van Accessible Self Parking
- Ramp Access
- Closed Caption TVs
- Telephone with TDD
- Visual Alarm/Alert in Guest Rooms
- Visual Alarm/Alert in Public Spaces
- Communication Kits with Visual Alarms
Provided by Hotel
Pet Policy + -
- Pets Allowed
- Service Animals Allowed
- Pet Walking Area On-site
- Pet Deposit per Stay: 50 USD
- 2 pet limit, 50lb limit, 50 dollars per stay, one time nonrefundable cleaning fee.
Facility + -
- Smoke-Free Facility
- Number of Floors: 4
- Total Number of Rooms: 78
- Number of Non-Smoking Rooms: 78
- Number of Accessible Rooms: 5
- Current Renovation: 18-March-2019 To 18-March-2020
- Public Spaces Renovated in: 2020
- Guest Rooms Renovated in: 2020
Languages + -
Languages Spoken by Staff
Credit Cards + -
- American Express
- Diners Club
- Carte Blanche
Be The Readiest® for your stay
2K Bonus Points Every 2 Nights
Medical/Hospital Personnel Discount
Military Appreciation Leisure Rate
Booking with confidence
FAQs for Holiday Inn Express Durham
How much is parking at Holiday Inn Express Durham?
Complimentary parking is available at Holiday Inn Express Durham for hotel guests.
Can I cancel my booking at Holiday Inn Express Durham for a full refund?
Yes, when you book your stay at Holiday Inn Express Durham direct with IHG, choose one of our flexible rates which include the flexibility to change or cancel your reservation at no charge. For full details, refer to our Travel Advisory details.
Does Holiday Inn Express Durham have a pool?
Yes, Holiday Inn Express Durham has an outdoor pool.
Is there free breakfast available at Holiday Inn Express Durham?
Yes, Holiday Inn Express Durham currently offers grab-and-go options for our complimentary breakfast.
When is breakfast at Holiday Inn Express Durham?
Breakfast at Holiday Inn Express Durham is available from 6:00 AM to 10:00 AM.
What are the check-in and check-out times for Holiday Inn Express Durham?
Check-in at Holiday Inn Express Durham is from 3:00 PM, and check-out time is 12:00 PM. Contact the hotel directly for options available for early check-in or late check-out.
Does Holiday Inn Express Durham offer free Wi-Fi?
Yes, the Holiday Inn Express Durham offers free WiFi!
Does Holiday Inn Express Durham have a restaurant on site?
No, there is no on site restaurant at Holiday Inn Express Durham.
Is there a fitness center at Holiday Inn Express Durham?
No, the Holiday Inn Express Durham does not have a fitness center on site.
How much does it cost to stay at Holiday Inn Express Durham?
Rates for accommodations at Holiday Inn Express Durham vary by season. For your rate options, please input your dates.
How many rooms does the Holiday Inn Express Durham have?
The Holiday Inn Express Durham has 78 guest rooms. Enter your dates to view available rooms for your stay.
Can I bring my pet to Holiday Inn Express Durham?
Pets are welcome at Holiday Inn Express Durham. There is a pet deposit per stay of 50 USD. Our Pet Policy: 2 pet limit, 50lb limit, 50 dollars per stay, one time nonrefundable cleaning fee..