Name: Vignette Collection Hotel Spero
Address: 405 Taylor Street, San Francisco, CA, 94102, United States
Telephone: 1-415-8852500
Price range: $$$ - Best Price Guarantee When You Book Direct

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Hotel Spero

Historic San Francisco, Boutique Hotel Charm

At Hotel Spero, discover a distinctive retreat tucked into the heart of vibrant Union Square. Steps from San Francisco’s most iconic neighborhoods, dining, attractions, and culture, the city unfolds just outside our hotel doors. Stroll to the Powell Street cable cars, enjoy a show in the Theater District or explore nearby Nob Hill and North Beach.

Inside, historic character blends effortlessly with modern design, creating a refined yet relaxed place to settle in, recharge, and explore. Whether you’re wandering the city for a weekend escape, savoring a slower stay, a business meeting or a meaningful celebration, Hotel Spero offers an inviting setting shaped by warmth, style, and intentional hospitality.

405 Taylor Street, San Francisco, CA 94102 United States

Contact Front Desk:
+1-415-885-2500

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Take a look inside

Lobby of Hotel Spero in Union Square San Francisco

Vignette Hotel Spero lobby

Hotel Lobby

Pet Friendly

Guest Room

Urban Suite living and dining areas at Hotel Spero in Union Square

Guest Room

Fitness Center featuring Peloton

Californian meeting room in Hotel Spero Union Square

Californian meeting space in San Francisco with U-shape setup

Exterior entrance of Hotel Spero in Union Square San Francisco

Hotel Highlights

A Curated Journey Through San Francisco
Stylish Slumber
Elevate Your Next Meeting or Event
Discover Artisanal Brews at Jasper's Corner
Embrace Union Square and San Francisco

A Curated Journey Through San Francisco

Experience San Francisco through curated itineraries that seamlessly blend iconic attractions, colorful neighborhoods, and exclusive local discoveries.

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Stylish Slumber

Relax in the sanctuary of our luxury San Francisco hotel rooms with warm lighting, and plush textiles. Chic geometric forms converge with cool designs and upscale touches to create a welcoming oasis.

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Elevate Your Next Meeting or Event

Perfectly crafted for hosting everything from an intimate dinner for 80 to a chic reception for 140, these spaces are meticulously designed to forge encounters as iconic as you. Our 3,000 square feet of Union Square meeting space is modern and versatile.

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Discover Artisanal Brews at Jasper's Corner

From elevated gastropub classics to cleverly crafted breakfast favorites, our eclectic award-winning menus dish out fusion-inspired flavor and organic ingredients that also cater to vegetarian palates.

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Embrace Union Square and San Francisco

Check in the heart of San Francisco. Our Union Square hotel's location offers effortless access to the city’s top attractions, cultural landmarks, and scenic sights. Enjoy easy access to the Chase Center, Chinatown, Market Street and the best of downtown.

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Spring flowers with Golden Gate Bridge in thr background

Spring Into San Francisco

From cherry blossoms and cultural festivals to scenic strolls and seasonal city adventures, discover the best of San Francisco this spring. Explore our guide to top events, blooming attractions, and must-see experiences just moments from Hotel Spero.

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Your Front-Row Stay for 2026’s Global Soccer Showdown

Let the spirit of the game echo beyond the stadium. Hotel Spero will be your downtown San Francisco sanctuary with easy access to Levi’s Stadium and a city alive with global energy and celebration.

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Catering to your every need

Our amenities and services are designed to ensure your stay is complete and you have easy access to the things you may need while you travel.

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Hotel packages available

Prices shown reflect an average per night stay from

Additional Offers

Carefully crafted accommodations

Standard

Our king rooms, recently upgraded, now feature luxurious glass-enclosed showers set against Spanish-tiled bathrooms, blending style and comfort. Each spacious room is elegantly furnished with a plush king-sized bed, a well-lit workspace, and oversized picture windows that bathe the space in natural

Suite

Include Serenity Suites, Urban Suites and one Bedroom Suites. All larger rooms with hardwood floors, 50 inch Television, WIFI, bath amenities, slippers, in-room safe, iron and ironing board, and a mini refrigerator.

Hotel Spero Accommodations

As the vibrant energy of the city settles for the day, make your way back to the comforting embrace of your Spero hotel room. Thoughtfully designed as a serene escape from the city's lively pace, each Union Square hotel room features warm ambient lighting, plush fabrics, and modern geometric accents. Sophisticated finishes and upscale details blend to create a welcoming oasis where relaxation comes naturally.

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{accoladesSource=TripAdvisor, accoladesTitle=Amazing customer service}

6191 - Hotel Accolade Source

Explore the extraordinary

San Francisco's Union Square is the teeming commercial hub of the city. A variety of shops and restaurants are packing into the area surrounding the actual square. Tourists huddle to view one the city's most unique sites, the manual cable car turnaround.

Local attractions

Map of Vignette Collection,405 Taylor Street,San Francisco,United States,94102

Hotel Spero

405 Taylor Street San Francisco CA, US

Check in - 3:00 PM, Check out - 12:00 PM
Parking is available at the garage next to the hotel.

TRANSPORTATION DETAILS

FAQs

Check-in at Hotel Spero is at 3:00 pm, and check-out is at 12:00pm.

Optional Note: Early check-in and late check-out may be available upon request and are subject to availability.

Hotel Spero is a 100% smoke-free property. Smoking is not permitted in guest rooms or public spaces.

Yes, Hotel Spero in Union Square offers a fully equipped fitness center with cardio machines, free weights, and strength equipment. Open daily 24/7 for your convenience.

No: In-room dining is not currently offered at Hotel Spero in Union Square, but our front desk can guide you to nearby dining options or help with restaurant reservations.

Yes, Hotel Spero offers a 24-hour business center with computers, printers, and office supplies to support your work needs while traveling.

For a more elevated work experience, guests can also enjoy Jarvis’ Corner Co-Working Space, a thoughtfully designed workspace ideal for focused productivity, collaboration, and creative thinking.

Yes, every time you stay at Hotel Spero, you’re now part of the extended IHG® family. As an IHG® One Rewards member, you can earn and redeem points in more ways than ever. Join Now.

Hotel Spero is just minutes from popular attractions like Union Sqaure,Chinatown, and the San Francisco Museum of Modern Art (SFMOMA). Whether you're exploring cultural sites or dining hotspots, our team can help you plan the perfect Union Square itinerary.For more information about nearby attractions, please visit: https://visitunionsquaresf.com/, https://www.sfmoma.org/

Hotel Spero is proud to support sustainable travel through eco-friendly practices like energy-efficient lighting, in-room recycling, water conservation systems, and locally sourced amenities.