St Louis International Airport (STL) : From the airport take I-70 East through downtown St. Louis to I-55 South. From I-55 take Hwy 67 South for approximately 2 hours to Hotel on Right.
Poplar Bluff Municipal Airport (POF) : Take 60 West to 67 North, and follow to the Hotel on the left.
Cape Girardeau Regional Airport (CGI) : South on I-55; West on US60; South on Business 67; Hotel on Right