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Holiday Inn Express & Suites Hannibal - Medical Center


Explore Hannibal

Don't Go Home Without

Don't go home without taking a stroll down Main Street, and visiting the local merchant shops. Antiques, specialty food and clothing stores, coffee shops, art galleries, and various souvenir shops line the street. Local restaurants and bars are also available to grab a bite to eat.

Must See

Enjoy breathtaking views beneath the Mark Twain Memorial Lighthouse located in Cardiff Hill Park. You will admire the mighty Mississippi River, and Historic Downtown Hannibal. At the base of Cardiff Hill on Main Street, see the bronze statues of Tom Sawyer and Huck Finn. This is a great place for pictures with two of Mark Twain's most memorable characters.

Must Do

Exciting attractions await in this historic river town! Explore the streets of Mark Twain's boyhood home, and visit the eight museums that are dedicated to him, and his famous characters. Visit the world famous Mark Twain Cave, and take a riverboat cruise down the Mighty Mississippi. Enjoy a live show, and stop to see the various art studios around town. Go to for more ideas

Local Tips

Hannibal is home to 8 museums dedicated Mark Twian, and his famous works. The Mark Twain Cave is Missouri's oldest show cave, and a visitor favorite. There are annual festivals, beautiful architecture, and riverboat excersions to enjoy. Historic Downtown has several restaurants, boutique shops, and galleries. You’ll also find great outdoor recreation throughout our parks.

Nearby Attractions

  • Mark Twain Cave