For centuries, people have been drawn to the Mississippi River and the surrounding prairies—to hunt, trade, farm, manufacture, and to live. Founded in 1867, the Putnam is one of the first museums established west of the Mississippi. The Putnam Museum of History and Natural Science offers permanent and changing exhibits, dynamic public programs, Giant Screen Theater, plus our exclusive Heritage Theater® and live interpretations. The largest museum in Quad Cities of eastern IA and western IL.