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Sikeston Hotels

Compare Hotels in Sikeston

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Finding a hotel is easy. Your destination can be:

  • a city (San Francisco)
  • an address (123 Main St., Springfield, IL)
  • an airport (LAX)
  • a point of interest (Fenway Park)
  • Zip Code (30308)

Featured Sikeston Hotels


115 Hospitality Drive

Sikeston, MO 63801

United States


Front Desk:


Candlewood Suites Cape Girardeau

City Center, 28.68 mi


485 South Mt. Auburn Road

Cape Girardeau, MO 63703

United States


Front Desk:


3253 William Street

Cape Girardeau, MO 63701

United States


Front Desk:

Whether it's your first visit or Sikeston is a favorite travel destination, get ready to explore all that Sikeston has to offer and find the perfect temporary home base with help from IHG. Our easy-to-navigate website allows you to compare the best hotels in Sikeston by reading through our honest 2428 reviews from verified hotel guests. When you book your room with IHG, you're assured a great deal and lowest rate with our Best Price Guarantee. We boast 3 hotels in Sikeston, MO, all with a distinctive flair and a variety of amenities, and you can conveniently narrow down your choices and book your room directly with us.

No matter if you're travelling to Sikeston to attend a conference, unwind on vacation, or enjoy a romantic weekend getaway, we have you covered. And if your travels take you to another part of the world, you'll find an IHG accommodation that meets your needs. From hotels in the heart of it all to luxury accommodations off the beaten path, IHG offers great hotel deals in Sikeston and throughout the world.

Enter your travel dates to view the best offers on hotel rooms, and use our advanced search features to find the hotels with the amenities you desire. When you stay as an IHG Rewards Club member, you also enjoy free in-hotel Internet access. Some of our hotels boast indoor swimming pools, while others offer hot breakfast, in-room kitchens, and spa services. We make it easy to book the perfect hotel for your trip.

Latest Sikeston Hotel Reviews

Missuori Stay
By Keith
The Cape Girardeau Holiday Inn Express was in excellent condition and the staff were very friendly. Would recommend to others. [Less]
Nice stay
By Fred86
Very nice place to stay. The hotel staff was very friendly, hotel clean and property safe. [Less]
Excellent stop when in cape girardeau
By Random guest
Business trip, all great at hotel, clean and be. No problems in any area, did not use pool or breakfast area- no problems, just didn’t use. [Less]
Comfortable mattress
By Just me
Easy check in, comfortable bed, convenient location near the highway. [Less]
Home away from home!
By DeepInTheHeartofTexas
I am basing this off being a contract healthcare professional and staying at this property for 6 months while on a job. It was everything I needed and wanted. Staff was extremely flexible and [More] helpful. I worked nightshift an they were very accommodating to cleaning my room first when they started so I could sleep in the afternoon and not have to be woken up for them to clean. I would highly recommend to anyone! [Less]
Great place for extended stays in Cape Girardeau
By travelerrn
I had the perfect room near the elevator. Quiet so conducive to sleep. Any issues attended to quickly. Was great to have pool and hot tub and the free laundry was a life saver. All the staff was [More] great and helpful. I will definitely stay there again if I work in Cape again [Less]
Stop at Lambert's
By Hawkeye515
Great location - very nice staff - Chocolate milk at breakfast (yea!) - close to Lambert's and that is a huge plus. [Less]
Great Place!
By AlJoyVoy
great staff, clean room, good breakfast, excellent place to stay at [Less]
Great Hotel
By John
Great location in Sikeston. Staff is very nice and professional. The breakfast bar at this location is the best I've experienced in the chain. [Less]

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